The presentation will provide an overview of a recently published National Academies of Sciences Research study. Information provides how state departments of transportation (DOTs) can develop and implement effective strategies for compliance with a National Pollutant Discharge Elimination System (NPDES) permit that includes a Total Maximum Daily Load (TMDL) requirement. State transportation agencies own and operate streets and highways that extends for many miles, and cross rivers/streams, waterbodies, watersheds, and jurisdictions. Transportation authorities are required through the Clean Water Act to manage the stormwater runoff that discharges to our nation’s waters through regulated municipal separate storm sewer systems (MS4s) along streets, roads, and highways. When a waterbody does not meet established water quality standards, State transportation agencies contributing to the water body impairment may be subject to the Section 303(d): Impaired Waters and Total Maximum Daily Loads (TMDLs) mandates.